New Liquid Chromatography (LC) Columns and Accessories

As in previous years, LCGC sent out a survey in late 2020 and early 2021 asking vendors to supply information on liquid chromatography (LC) columns and accessories launched after Pittcon 2020. Information for this article was obtained over the course of several months, and thus, it is possible that some information has been missed or misinterpreted. The reader is encouraged to check with specific vendor sites for additional products, as well as more detailed information on product usage and attributes.
The vendors that responded to the survey and their new LC products are listed in Table 1. The products vary in targeted analyte type, as well as in their mode of chromatographic operation. The columns can be initially categorized as addressing small molecule or large molecule challenges. Within these categories, the products can be further separated based on specific modes of separation employed, including reversed‑phase LC, hydrophilic interaction liquid chromatography (HILIC), hydrophobic interaction chromatography (HIC), size-exclusion chromatography (SEC), and ion-exchange chromatography (IEC). Chiral columns are treated as a separate category. In addition to new chromatographic columns, accessories related to LC are also addressed. Trends noted throughout the article are based on comparisons to yearly reports since 2016 (1–5). In the 2020 LC product review, the number of vendors reporting new products as well as the overall number of products showed a sharp downturn over previous years. Table 2 provides a breakdown of products introduced in various categories over the previous five years plus this most recent year. The data suggests that the low numbers observed in the 2020 review was an anomaly, and not the beginning of a downward trend. The number of reporting vendors in 2021 is still low relative to some recent years; however, the number of unique column chemistries released is back on par with the previous five years of data. Please note that many products can be categorized in multiple areas, depending on usage. This is meant to be a basic guide that highlights trends only. Columns targeting reversed-phase analysis of small molecules represent the largest group of newcomers (columns ascribed for peptide and oligonucleotide analysis were grouped with the small molecule columns). Characterization of large molecules often requires the use of multiple modes of separation. The new columns launched over the past year for the analysis of large molecules targeting reversed-phase, SEC, HIC, and IEC reflect that need.
Thanks and regards,
Jessey
Managing Editor
Whatsapp- +3225889658
As in previous years, LCGC sent out a survey in late 2020 and early 2021 asking vendors to supply information on liquid chromatography (LC) columns and accessories launched after Pittcon 2020. Information for this article was obtained over the course of several months, and thus, it is possible that some information has been missed or misinterpreted. The reader is encouraged to check with specific vendor sites for additional products, as well as more detailed information on product usage and attributes.
The vendors that responded to the survey and their new LC products are listed in Table 1. The products vary in targeted analyte type, as well as in their mode of chromatographic operation. The columns can be initially categorized as addressing small molecule or large molecule challenges. Within these categories, the products can be further separated based on specific modes of separation employed, including reversed‑phase LC, hydrophilic interaction liquid chromatography (HILIC), hydrophobic interaction chromatography (HIC), size-exclusion chromatography (SEC), and ion-exchange chromatography (IEC). Chiral columns are treated as a separate category. In addition to new chromatographic columns, accessories related to LC are also addressed. Trends noted throughout the article are based on comparisons to yearly reports since 2016 (1–5). In the 2020 LC product review, the number of vendors reporting new products as well as the overall number of products showed a sharp downturn over previous years. Table 2 provides a breakdown of products introduced in various categories over the previous five years plus this most recent year. The data suggests that the low numbers observed in the 2020 review was an anomaly, and not the beginning of a downward trend. The number of reporting vendors in 2021 is still low relative to some recent years; however, the number of unique column chemistries released is back on par with the previous five years of data. Please note that many products can be categorized in multiple areas, depending on usage. This is meant to be a basic guide that highlights trends only. Columns targeting reversed-phase analysis of small molecules represent the largest group of newcomers (columns ascribed for peptide and oligonucleotide analysis were grouped with the small molecule columns). Characterization of large molecules often requires the use of multiple modes of separation. The new columns launched over the past year for the analysis of large molecules targeting reversed-phase, SEC, HIC, and IEC reflect that need.
Thanks and regards,
Jessey
Managing Editor
Whatsapp- +3225889658