The term natural products is often used synonymously with secondary metabolite. It is a chemical compound or substance produced by a living organism found in nature that usually has a pharmacological or bio activity to be used in drug discovery process. Natural products played a vital role on this earth, so man’s existence has been made possible. The outstanding phenomenon of nature always stands as golden mark for achieving the herbal drug discovery. From earlier decades medicinal plants existed on earth. Thus, medicinal herbs are of global and paramount importance. The world is decorated with medicinal herbs, which is a rich wealth of endurance. Every plant is identified by its own different therapeutic properties due to active bioactive molecule. In the modern system of medicine, natural drug substances are reported to be vital and have appreciable roles. Their therapeutic role was justified by the presence of their bioactive mol-ecules. Due to disease-inhibiting capabilities, they are extremely useful as natural drugs, provide basic bioactive compounds that are less toxic and more effective, and bring biological and chemical means of modification and extraction of natural products into potent drug. The raw materials for Ayurveda medicines were mostly obtained from plant sources in the form of crude drugs such as dried herbal powders or their extracts or mixture of products. Apart from these systems, there has been a rich heritage of ethno botanical usage of herbs by various colorful tribal communities in the country. It has been estimated that nearly species of higher plants exist on the earth, and only have been used in traditional medicine. Only to have been studied scientifically and are known to have therapeutic value. Around the globe, herbal medicine is based on traditional medicine. As per the oral survey made in many regions of the world, it has been said that traditional medicines have their own importance and basic philosophy. So exploration of the chemical constituents of the plants and their pharmacological screening may pro-vide us the basis for developing a lead molecule through herbal drug discovery. The very important life-saving drugs have been provided by herbs in modern medicine. But among the estimated -lakh plant species only have been studied for their activity and very less not more than of have been investigated phytochemicals. Thus, there is a need of investigating the various bioactive fractions and the phytoanalysis and phytopharmacological evaluation of herbal drugs for achieving the dreams of herbal drug discovery. Many people believe that products labeled "natural" are always safe and good for them. This is not necessarily true. Herbal medicines do not have to go through the testing that drugs do. Some herbs, such as comfrey and ephedra, can cause serious harm. Natural ingredients include plant, animal, mineral and/or microbial ingredients present in (or produced by) nature. Natural ingredients may also be directly extracted using simple methods (like simple chemical reactions) or they may be the result of naturally occurring biological processes. Acetaminophen the active ingredient in many Americans’ goes-to pain reliever, Tylenol typically stems from a surprising source: coal tar, a viscous liquid produced when oxygen-deprived coal is subjected to high heat.

Best Regards,
Nancy Ella
Editor-In-Charge
Drug Designing: Open Access