We confirmed that adding Amerchol L101 to lanolin alcohol in routine patch testing has an additional diagnostic value in detecting lanolin contact allergy. We reported a higher prevalence of patients with lanolin contact allergy (28.6%, 95% CI: 25.1%-32.3%) than normally reported. Our study population consisted of patients with a high suspicion of lanolin contact allergy, as they were selected to be additionally tested with lanolin derivatives. Moreover, the patients were referred for tertiary care. The positive association between atopic dermatitis and lanolin contact allergy has previously been reported. The association between an age of <40 years and lanolin contact allergy was not in line with the literature, as previous studies reported a positive association between higher age and lanolin contact allergy [3,7]. The patch test concentration and/or the vehicle of some lanolin derivatives are not perfect. In addition, the relevance of a positive patch test reaction to lanolin can be difficult to establish. Further research is necessary to improve the patch test concentration of lanolin derivatives and better define the clinical relevance of positive patch tests. >. A retrospective analysis of patients patch tested between 2016 and 2017 was performed. Patients were eligible if tested with lanolin alcohol 30% PET., Amerchol L101 50% PET. and a supplementary series containing other lanolin derivatives (e.g. cetearyl alcohol, adeps lanae, and Eucerin). Lanolin alcohol and Amerchol L101 were tested in duplicate

Journal of Dermatitis is using Editorial Tracking System for quality in review process. Editorial Tracking is an online manuscript submission, review and tracking systems used by most of the best open access journals. Review processing is performed by the editorial board members of journal or outside experts; at least two independent reviewers approval followed by editor's approval is required for acceptance of any citable manuscript.

Authors are requested to submit manuscripts online or send as an e-mail attachment to the Editorial Office at manuscripts@longdom.org