Chemotherapy is a type of cancer treatment that uses one or more anti-cancer drugs  as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent , or it may aim to prolong life or to reduce symptoms. Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called medical oncology.

The term chemotherapy has come to connote non-specific usage of intracellular poisons to inhibit mitosis  or induce DNA damage, which is why inhibition of DNA repair can augment chemotherapy. The connotation of the word chemotherapy excludes more selective agents that block extracellular signals. The development of therapies with specific molecular or genetic targets, which inhibit growth-promoting signals from classic endocrine hormones are now called hormonal therapies. By contrast, other inhibitions of growth-signals like those associated with receptor tyrosine kinases are referred to as targeted therapy. Importantly, the use of drugs constitutes systemic therapy for cancer in that they are introduced into the blood stream and are therefore in principle able to address cancer at any anatomic location in the body.

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With Regards,

Anna D Parker

Editorial Assistant

Journal of pharmaceutica Analytica Acta

Email: pharmaanalytica@engjournals.com